Preparation and characterization of gac loadedcellulose acetate nanofiber patch
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Creator 1. Natyada Khammanewanitwong
2. Ratthapol Rangkupan
3. Pornpen Werawatganone
Title Preparation and characterization of gac loadedcellulose acetate nanofiber patch
Publisher Research and Development Office, Prince of Songkla University
Publication Year 2564
Journal Title Songklanakarin Journal of Science an Technology (SJST)
Journal Vol. 43
Journal No. 5
Page no. 1252-1258
Keyword gac extract, beta-carotene, nanofiber, patch, characterization
URL Website https://rdo.psu.ac.th/sjst/index.php
ISSN 0125-3395
Abstract The aims of this study were to fabricate cellulose acetate (CA) nanofiber patch containing gac extract usingelectrospinning process, and to characterize and investigate release and stability of the patch. The patch was successfullyprepared using electrospinning process from 17% w/v CA and 3.40% w/v gac extract dissolved in 2:1 v/v acetone/dimethylacetamide. Diameter of the obtained nanofibers of the patch was 341?63 nm and the gac extract was entrapped well inthe nanofibers. Burst release was observed in the release profile of beta-carotene in the extract from the patch and approximately62 % of beta-carotene was released in an hour. The beta-carotene content in the nanofiber patch remained 50% of the initialamount after 6 months at 40?C and 75%RH, while the physical properties of nanofiber patch were unchanged. This study mayenhance the use of gac-loaded CA nanofiber patch and the applications of nanofibers for cosmetic purpose.
Songklanakarin Journal of Science and Technology (SJST)

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