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Microwave-assisted extraction of Dendrobium nobile Lindl.and its ?-glucosidase inhibitory activity |
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| รหัสดีโอไอ | |
| Creator | 1. Chattarika Pengdee 2. Boonchoo Sritularak 3. Waraporn Putalun |
| Title | Microwave-assisted extraction of Dendrobium nobile Lindl.and its ?-glucosidase inhibitory activity |
| Publisher | Research and Development Office, Prince of Songkla University |
| Publication Year | 2563 |
| Journal Title | Songklanakarin Journal of Science and Technology |
| Journal Vol. | 42 |
| Journal No. | 6 |
| Page no. | 1304-1309 |
| Keyword | Dendrobium nobile, microwave-assisted extraction, Taguchi, ?-glucosidase inhibitory activity |
| URL Website | https://rdo.psu.ac.th/sjstweb/index.php |
| ISSN | 0125-3395 |
| Abstract | Diabetes mellitus (DM) is an important metabolic disease due to its worldwide increasing prevalence. Dendrobiumnobile Lindl. is used in traditional Chinese medicine and has been reported to have antidiabetic activity. In this study, severalextraction methods, including microwave-assisted extraction (MAE), were applied to D. nobile and the extracts were investigatedfor ?-glucosidase inhibition potency. The optimal MAE conditions maximizing ?-glucosidase inhibition were 540 W power, 60sec extraction time, 40 mL/g solvent-to-feed ratio, and three extraction cycles. Our results show that MAE of D. nobile gavestronger inhibition of ?-glucosidase with lower IC50 and faster extraction than the other extraction methods. IC50 of D. nobileextract was related to phenolic content with correlation -0.878, indicating that phenolics were the active compounds inhibiting ?glucosidase in these plant extracts. |
