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Antimicrobial electrospun fiber mat from gelatinand crude extract of lipopeptides |
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รหัสดีโอไอ | |
Creator | 1. Tipnipa Yoochang 2. Jirarat Anuntagool 3. Suthep Thaniyavarn 4. Masaaki Morikawa 5. Jiraporn Thaniyavarn |
Title | Antimicrobial electrospun fiber mat from gelatinand crude extract of lipopeptides |
Publisher | Research and Development Office, Prince of Songkla University |
Publication Year | 2563 |
Journal Title | Songklanakarin Journal of Science and Technology |
Journal Vol. | 42 |
Journal No. | 1 |
Page no. | 101-108 |
Keyword | biosurfactant, lipopeptides, gelatin, nanofiber, antimicrobial mat |
URL Website | https://rdo.psu.ac.th/sjstweb/index.php |
ISSN | 0125-3395 |
Abstract | Lipopeptides from Bacillus subtilis represent a class of biosurfactants with increasing therapeutic and biotechnologicalinterests. In this study, we added crude extract of lipopeptides into a gelatin solution to examine the effect of these crudelipopeptides using electrospinning. The addition of crude lipopeptides to a gelatin solution affected the solution viscosity andconductivity and resulted in a decrease in nanofiber diameter when the solution was electrospun to produce nanofibers.Crosslinking of nanofibers using saturated glutaraldehyde for 10 and 30 min improved the mechanical properties and waterretention capacity of the mats formed from the nanofibers. Furthermore, the lipopeptides-loaded nanofiber mats showedantibacterial activity toward Staphylococcus aureus ATCC 6538P. |