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The interaction effect of ginger extract and ascorbic acidon antioxidant activity |
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รหัสดีโอไอ | |
Creator | 1. Apakorn Singprecha 2. Liudmila Yarovaya 3. Watcharee Khunkitti |
Title | The interaction effect of ginger extract and ascorbic acidon antioxidant activity |
Publisher | Research and Development Office, Prince of Songkla University |
Publication Year | 2563 |
Journal Title | Songklanakarin Journal of Science and Technology |
Journal Vol. | 42 |
Journal No. | 4 |
Page no. | 850-857 |
Keyword | ginger extract, ascorbic acid, antioxidant, antagonism, interaction |
URL Website | https://rdo.psu.ac.th/sjstweb/index.php |
ISSN | 0125-3395 |
Abstract | The antioxidant effects of individual natural compounds have been extensively investigated. However, studies on theirinteractions are still lacking. This study aimed to observe the interaction effect of ginger extract (GE) combined with ascorbicacid on antioxidant activity by applying response surface methodology. The results from the quadratic model showed thatindividually tested DPPH free radical scavenging capacities of GE and ascorbic acid manifested positive effects on theantioxidant index (AI%). However, interaction of their combination demonstrated an antagonistic effect that negativelyinfluenced the AI%. An optimization process revealed that the highest AI% could be achieved by applying maximum effectiveconcentrations of GE (0.49 mg/mL) and ascorbic acid (0.82 mg/mL). Although, the mechanisms behind these interactions need tobe further explored, the results of this study suggested that antagonistic interaction between the combination of ginger or otherherbal extracts with ascorbic acid should be taken into consideration to prevent any potential health complications. |