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Oxidative stress biomarkers and complexity of heart rate variability during acute single cigarette smoking |
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| รหัสดีโอไอ | |
| Creator | 1. Amornchai Trikunakornwong 2. Kesorn Suwanprasert |
| Title | Oxidative stress biomarkers and complexity of heart rate variability during acute single cigarette smoking |
| Publisher | Research and Development Office, Prince of Songkla University |
| Publication Year | 2562 |
| Journal Title | Songklanakarin Journal of Science and Technology |
| Journal Vol. | 41 |
| Journal No. | 3 |
| Page no. | 599-606 |
| Keyword | heart rate variability, autonomic system, nitric oxide, sLOX-1, smoking |
| URL Website | http://rdo.psu.ac.th/sjstweb/index.php |
| ISSN | 0125-3395 |
| Abstract | Smoking causes sympathovagal changes and peripheral vessel injury, which can be assessed by heart rate variability (HRV) that includes endothelial nitric oxide (NO) and sLOX-1 markers, respectively. This study aimed to investigate the HRV and NO changes in acute smoking and sLOX-1 overproduction in chronic smoking. A total of 60 males were recruited. Thirty smokers and 30 non-smokers were studied. At first the HRV parameters were obtained from all subjects. Only smokers were then consecutively recorded for 5 min and 15 min after smoking a single cigarette with simultaneous blood collection at each time point for NO and sLOX-1 measurements. We found a significant lowering of HRV and a positive correlation between sLOX-1 and mean arterial pressure in smokers. After 5 min of smoking, an immediate adverse effect of autonomic function was represented by the HRV along with an immediate lowering of NO which is a vasodilator. Acute smoking influences the autonomic neural control from NO-mediated modulation which can be assessed by the noninvasive technique of HRV analysis. |
