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Pharmacognostic and physico-chemical investigations of the aerial part of Bacopa monnieri (L.) Wettst. |
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| รหัสดีโอไอ | |
| Creator | 1. Tongchai Saesong 2. Prapapan Temkitthawon 3. Pranee Nangngam 4. Kornkanok Ingkaninan |
| Title | Pharmacognostic and physico-chemical investigations of the aerial part of Bacopa monnieri (L.) Wettst. |
| Publisher | Research and Development Office, Prince of Songkla University |
| Publication Year | 2562 |
| Journal Title | Songklanakarin Journal of Science and Technology |
| Journal Vol. | 41 |
| Journal No. | 2 |
| Page no. | 397-404 |
| Keyword | Bacopa monnieri (L.) Wettst, Brahmi, monograph, pharmacognostic study, HPLC fingerprint |
| URL Website | http://rdo.psu.ac.th/sjstweb/index.php |
| ISSN | 0125-3395 |
| Abstract | A macroscopic, microscopic, physico-chemical, and phytochemical analysis of the aerial part of Bacopa monnieri (L.) Wettst. or Brahmi was undertaken for the purpose of establishing a monograph. The macroscopic and microscopic studies presented the typical characteristics of the Brahmi plant and its powder. The standard values of physico-chemical parameters were established at not more than 10.0 %w/w for loss on drying and 13.0 %w/w for total ash as well as not less than 17.0 %w/w for water soluble extractives and 10.0 %w/w for ethanol soluble extractives. Phytochemical analysis showed the presence of steroidal saponins, with confirmation by the TLC fingerprint. Total saponin content was not less than 1.0 %w/w measured by HPLC-UV method. The overall study provides pharmacognostical, physico-chemical, phytochemical details, typical TLC and HPLC fingerprints of the Brahmi, which can be used to establish a Pharmacopoeia monograph for the identification and standardization of Brahmi material. |
