Periostin staining within renal tissues from IgA nephropathy patients
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Creator 1. Peepattra Wantanasiri
2. Bancha Satirapoj
3. Mongkon Charoenpitakchai
4. Pornanong Aramwit
Title Periostin staining within renal tissues from IgA nephropathy patients
Publisher Research and Development Office, Prince of Songkla University
Publication Year 2561
Journal Title Songklanakarin Journal of Science and Technology
Journal Vol. 40
Journal No. 1
Page no. 155
Keyword Periostin staining, IgA nephropathy, periglomerular staining, tubular cell cast staining, tubular epithelial cellstaining
URL Website http://rdo.psu.ac.th/sjstweb/index.php
ISSN 0125-3395
Abstract Periostin is a novel biomarker related to kidney disease progression. The aim of this study was to examine thelevel of periostin staining within renal tissue from IgA nephropathy patients. Immunohistochemistry for periostin wasperformed. The score of periostin staining and the correlation of periostin staining score with each pathological feature wereevaluated. Positive periostin staining was found in renal tissue from IgA nephropathy patients including glomerular,interstitial, vascular and tubular areas. Tubular epithelial cell staining, tubular cell cast staining and periglomerular stainingwere common histologic features positive for periostin. Periglomerular staining were correlated with interstitial fibrosis aswell as with tubular epithelial cell staining. In addition, tubular cell cast staining were correlated with tubular epithelial cellstaining as well as with tubular atrophy staining. We concluded that periostin may be a promising biomarker in IgAnephropathy patients.
Songklanakarin Journal of Science and Technology (SJST)

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