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Periostin staining within renal tissues from IgA nephropathy patients |
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รหัสดีโอไอ | |
Creator | 1. Peepattra Wantanasiri 2. Bancha Satirapoj 3. Mongkon Charoenpitakchai 4. Pornanong Aramwit |
Title | Periostin staining within renal tissues from IgA nephropathy patients |
Publisher | Research and Development Office, Prince of Songkla University |
Publication Year | 2561 |
Journal Title | Songklanakarin Journal of Science and Technology |
Journal Vol. | 40 |
Journal No. | 1 |
Page no. | 155 |
Keyword | Periostin staining, IgA nephropathy, periglomerular staining, tubular cell cast staining, tubular epithelial cellstaining |
URL Website | http://rdo.psu.ac.th/sjstweb/index.php |
ISSN | 0125-3395 |
Abstract | Periostin is a novel biomarker related to kidney disease progression. The aim of this study was to examine thelevel of periostin staining within renal tissue from IgA nephropathy patients. Immunohistochemistry for periostin wasperformed. The score of periostin staining and the correlation of periostin staining score with each pathological feature wereevaluated. Positive periostin staining was found in renal tissue from IgA nephropathy patients including glomerular,interstitial, vascular and tubular areas. Tubular epithelial cell staining, tubular cell cast staining and periglomerular stainingwere common histologic features positive for periostin. Periglomerular staining were correlated with interstitial fibrosis aswell as with tubular epithelial cell staining. In addition, tubular cell cast staining were correlated with tubular epithelial cellstaining as well as with tubular atrophy staining. We concluded that periostin may be a promising biomarker in IgAnephropathy patients. |