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Microencapsulation of citronella oil for mosquito repellent:Preparation and evaluation of release characteristics |
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| รหัสดีโอไอ | |
| Creator | 1. Sarunyoo Songkro 2. Pichayakarn Yapong 3. Pimrat Puechpan 4. Duangkhae Maneenuan 5. Prapaporn Boonme |
| Title | Microencapsulation of citronella oil for mosquito repellent:Preparation and evaluation of release characteristics |
| Publisher | Research and Development Office, Prince of Songkla University |
| Publication Year | 2561 |
| Journal Title | Songklanakarin Journal of Science and Technology |
| Journal Vol. | 40 |
| Journal No. | 4 |
| Page no. | 767 |
| Keyword | citronella oil, coacervation, microcapsule, mosquito |
| URL Website | http://rdo.psu.ac.th/sjstweb/index.php |
| ISSN | 0125-3395 |
| Abstract | The major aims of the current study were to prepare citronella oil microcapsules using the complex coacervationtechnique and evaluate the in vitro release properties of citronella oil from the prepared microcapsules. Gelatin and acacia, whichare oppositely charged polymers, were chosen as the wall materials and the core substance was citronella oil produced by steamdistillation of Cymbopogan winterianus. Formaldehyde was employed as a hardening agent. The core-to-wall ratio was fixed at1:2, whereas the gelatin-to-acacia ratio, concentration of citronella oil, amount of hardening agent, and hardening time werevaried. Among 18 formulations studied, three formulations produced satisfactory appearances of white microcapsules. Scanningelectron microscopy revealed that the microcapsules were discrete and spherical in shape. Microcapsules with the smoothestsurfaces were achieved in formulation F13 containing a 1:1 gelatin: acacia ratio. The percentages of oil content in formulationsF13, F14, and F15 were 25.41?1.42%, 24.94?1.31%, and 19.89?1.31%, respectively. Simple diffusion cells with a syntheticmembrane were used to study the in vitro release of citronella oil from the microcapsules. The release kinetics of citronella oilwas also examined. The release data of citronella oil followed the Higuchi model with a high coefficient of determination values(r2>0.97). Formulation F13 had the greatest release rate of citronella oil (P<0.05), while the release rate of formulation F14 wascomparable to that of formulation F15. In conclusion, the potential microcapsule formulation for mosquito repellency wasformulation F14, owing to its relatively high percentage of oil content and relatively slow release rate. The rapid volatility ofcitronella oil would be potentially reduced with the slow release properties. |
