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Causality pattern of the blood lead, monoamine oxidase A, and serotonin levelsin brass home industry workers chronically exposed to lead |
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| รหัสดีโอไอ | |
| Creator | 1. Aditya Marianti 2. A. Anies 3. Henna Rya Sunoko Abdurachim |
| Title | Causality pattern of the blood lead, monoamine oxidase A, and serotonin levelsin brass home industry workers chronically exposed to lead |
| Publisher | Research and Development Office, Prince of Songkla University |
| Publication Year | 2559 |
| Journal Title | Songklanakarin Journal of Science and Technology (SJST) |
| Journal Vol. | 38 |
| Journal No. | 2 |
| Page no. | 147-153 |
| Keyword | chronic lead exposure,blood lead level,MAO A level,serotonin level,brass industry workers |
| ISSN | 0125-3395 |
| Abstract | The present study aims to analyse the effects of lead (Pb) chronic exposure on blood lead levels, Monoamine oxidaseA enzyme (MAO A) and serotonin levels of brass craftsmen in Pati, Central Java, Indonesia, and to examine the connectionsamong these three variables. The brass home industry area was polluted by lead. Thus, it chronically exposes the workers tolead pollution. Therefore, their blood lead level increased and later raised the level of MAO A and reduced the level of serotonin.Path analysis results show that the path coefficient (?) of lead effects in decreasing serotonin through MAO A pathway is-0.411. Furthermore, lead effects that directly affect serotonin level without passing through MAO A pathway is -0.391 withresidual coefficient (e) of 0.572. In conclusion, the increase of blood lead level causes an increase in level of MAO A anddrop in the level of serotonin. |
